1

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay. 

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Ravi A, Palamiuc L, Loughran RM, Triscott J, Arora GK, Kumar A, Tieu V, Pauli C, Reist M, Lew RJ, Houlihan SL, Fellmann C, Metallo C, Rubin MA, Emerling BM.  Dev Cell. 2021 Jun 7;56(11):1661-1676.e10. 

2

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).  

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Klionsky DJ et al. Autophagy. 2021 Jan;17(1):1-382.

3

ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer.

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Renne MF, Emerling BM.  J Cell Biol. 2020 Jan 6;219(1). 

4

Phosphoinositides in Autophagy: Current Roles and Future Insights.

Palamiuc, L , Ravi, A and Emerling, BM (2019). FEBS J. 2019.

5

PSMA brings new flavors to PI3K signaling: A role for glutamate in prostate cancer.

Palamiuc, L and Emerling, BM (2018). JEM. 2018; 215(1):17-29.

6

Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy.

Lundquist MR, Goncalves MD, Loughran RM, Possik E, Vijayaraghavan T, Yang A, Pauli C, Verma A, Yang Z, Johnson JL, Wong JCY, Ma Y, Weinkove D, Divecha N, Asara JM, Elemento O, Rubin MA, Kimmelman AC, Pause A, Cantley LC, and Emerling BM. (2018) Mol Cell. 70(3): 531-544. 

7

PIP-ing Lipids on Membranes: PTEN takes the cake.

Ravi A and Emerling, BM. (2017). Mol Cell. 2017; 68(3):471-472.

8

Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune system.

Shim H, Wu C, Ramsamooj S, Bosch KN, Chen Z, Emerling BM, Yun J, Liu H, Choo-Wing R, Yang Z, Wulf GM, Kuchroo VK, and Cantley LC. (2016) Proc Natl Acad Sci U S A. Jul 5; 113(27): 7596-601.

9

The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

Sumita K, Lo YH, Takeuchi K, Senda M, Kofuji S, Ikeda Y, Terakawa J, Sasaki M, Yoshino H, Majd N, Zheng Y, Kahoud ER, Yokota T, Emerling BM, Asara JM, Ishida T, Locasale JW, Daikoku T, Anastasiou D, Senda T, and Sasaki AT. (2016) Mol Cell. Jan 21; 61(2): 187-98.

10

Depletion of a Putatively Druggable Class of Phosphatidylinositol Kinases Inhibits Growth of p53 Null Tumors.

Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Wulf G, Bell EL, Shim H, Choo-Wing R, Bellinger G, Lamia KA, Rameh LE, Sasaki A, Asara JM, Yuan X, Bullock A, Brown V, Signoretti S, and Cantley LC. (2013) Cell. Nov 7; 155(4): 844-57.

11

A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.

Davis MI, Sasaki A, Shen M, Emerling BM, Cantley LC, Thorne N, Li Z, Pragani R, Boxer M, and Simeonov A. (2013) PLOS ONE. 8(1):e54127.